一般是一个项目有问题,重启系统之后会OK的.如果还是不行,可以把WINCC删除重装,请注意一定也要把SYBASE数据库重装.因为官方资料上说是WINCC数据库的安全模式有问题.
对了,你的是5.0的版本的还是6.0版本的?6.0版本的话可以查看以下的文章:
QUESTION:
Why do I receive an "HResult Error 0x80046127" when opening a SIMATIC WinCC V6 project ?
ANSWER:
The HResult Error occurs if the security mode of the SQL-Server was changed from "Mixed Mode" to "Windows Authentication Only".
WinCC uses a SQL-Server-Login in order to establish a connection to the SQL-Database. If the security mode is changed to "Windows Authentication Only", WinCC can no longer access these databases.
The following steps show how to change the security mode of the SQL-Server to "Mixed Mode".
Setting up "Mixed Mode":
1. Open the SQL Server Enterprise Manager via Start > Programs > Microsoft SQL Server > Enterprise Manager.

2. Extend the "SQL Server Group" positioned on the left side of the navigation window by clicking on the + symbol.

3. Use the right mouse button to click on (\WinCC) and select Properties.

4. Change to tab Security.

5. Select Authentication > SQL Server and Windows.

6. Confirm the requests to restart the SQL-Server.

7. Now it is possible again to open projects with WinCC